电影个故事相互穿插而成，一个毒贩与一年轻女子偷尝禁果后闹出人命；因为一个酒精、毒品、药物作祟的夜晚，四个航空机舱人员为了一个又一个盖不住的谎言而酿成大错；两个欲改过自新的骗子，却阴差阳错陷入了一场杀生之祸。一连串看似相连又不相干的人事物，因为身边所有连锁反应，扭转了周遭一系列纠缠不清的命运交错。每一个起因变化，都会导致不一样的结局。
"Twisted" revolves around a drug dealer who banged up a young girl, a pair of con men who wants to turn over a new leaf, and four cabin crews whose lives were turned upside down over a fateful night of drugs and booze. This is a story of individuals with fates intertwined and how their paths clash - a series of twisted events that is both a study on cause and effect, and how our actions affect the people around us.
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